Alpha-halocarboxylic acids and derivatives
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Filtered Search Results
Cayman Chemical FTI276 trifluoroacetate salt
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A peptidomimetic inhibitor of FTase (IC50 = 500 pM); selective for FTase over GGTase I (IC50 = 50 nM); inhibits the growth of NIH3T3 cells expressing RasF at 20 µM; reduces tumor growth in a mouse xenograft model using Calu-1 cells that contain a K-Ras oncogenic mutation
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eMolecules BENZYL 2-BROMOACETATE 10G
5000162639 BENZYL 2-BROMOACETATE 10G
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Selleck Chemical LLC RR82 Trifluoroacetate Salt
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Pyridostatin Trifluoroacetate Salt is a G-quadruplexe stabilizer with Kd of 490 nM in a cell-free assay which targets a series of proto-oncogenes
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Cayman Chemical W146 trifluoroacetate salt
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An S1P1 receptor antagonist (Ki = 77 nM); selective for S1P1 over S1P2, S1P3, and S1P5 (Kis = >10 µM); prevents ligand-induced receptor internalization in CHO cells and inhibits ERK and Akt phosphorylation at 10 µM; increases AMD3100-induced KSL-HSPC entrance into mouse blood circulation from the bone marrow at 5 mg/kg in combination with AMD3100; disrupts the endothelial barrier and induces PMN neutrophil infiltration into the lungs and skin in an ovalbumin-induced mouse model of immune cell-mediated vascular injury at 10 UG intranasally or intradermally
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eMolecules SODIUM TRIFLUOROACETATE 25G
5000160367 SODIUM TRIFLUOROACETATE 25G
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Chem-Impex International, Inc. Ethyl difluoroacetate | MFCD00013578 | 25G
Ethyl difluoroacetate, MFCD00013578, 25G
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eMolecules SODIUM TRIFLUOROACETATE 100G
5000161008 SODIUM TRIFLUOROACETATE 100G
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Cambridge Isotope Laboratories Tauro-beta-muricholic acid sodium salt (unlabeled) CP 95% 1 mg
Tauro-beta-muricholic acid sodium salt (unlabeled) CP 95% 1 mg
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000374838 ODN 2216 SODIUM 1MG
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eMolecules SODIUM TRIFLUOROACETATE 25G
5000159101 SODIUM TRIFLUOROACETATE 25G
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eMolecules SODIUM TRIFLUOROACETATE 100G
5000164740 SODIUM TRIFLUOROACETATE 100G
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Cayman Chemical W146 trifluoroacetate salt
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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An S1P1 receptor antagonist (Ki = 77 nM); selective for S1P1 over S1P2, S1P3, and S1P5 (Kis = >10 µM); prevents ligand-induced receptor internalization in CHO cells and inhibits ERK and Akt phosphorylation at 10 µM; increases AMD3100-induced KSL-HSPC entrance into mouse blood circulation from the bone marrow at 5 mg/kg in combination with AMD3100; disrupts the endothelial barrier and induces PMN neutrophil infiltration into the lungs and skin in an ovalbumin-induced mouse model of immune cell-mediated vascular injury at 10 UG intranasally or intradermally
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Strem, An Ascensus Company CAS# 383-63-1. 25g. Ethyltrifluoroacetate, 99%. MFCD00000419
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CAS# 383-63-1. 25g. Ethyltrifluoroacetate, 99%. MFCD00000419. Molecular Weight: 142.08. Molecular Formula: CF3CO2C2H5. Color/form: colorless liq. Strem# 09-3270. http://www.strem.com/catalog/v/09-3270/
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eMolecules TERT-BUTYL BROMOACETATE 25G
5000170648 TERT-BUTYL BROMOACETATE 25G
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AdipoGen GE23077 A1 B1
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Chemical. CAS 752989-46-1, 752989-45-0752989-44-9. Formula C31H51N9O16, C31H49N9O16. MW 805.8803.8. Isolated from Actinomadura sp. Cyclic heptapeptide antibiotic. Potent and selective inhibitor of bacterial RNA polymerase RNAP. Inhibits Gram-positive Bacillus subtilis and Gram-negative Escherichia coli RNAPs with IC50 ~20nM, whereas it is not active on E. coli DNA polymerase or on eukaryotic wheat germ RNAP II IC50 values >100µM. Even though of its potent activity in vitro on purified bacterial RNAPs, it shows a narrow spectrum of antimicrobial activity in vivo on Gram-positive and Gram-negative bacteria, due to lack of memmbrane permeability. Acts at the level of transcription initiation. Binds directly to the bacterial RNA polymerase RNAP active-center i and i1 nucleotide binding sites, preventing the binding of initiating nucleotides and thereby preventing transcription initiation.
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